منابع مشابه
Cytology of Immunologic Memory
Pairs of rats were immunized with keyhole limpet hemocyanin (KLH) and simultaneously labeled with thymidine-methyl-(3)H or 5-iodo-2'-deoxyuridine-(125)I. From 10-50 days later, their lymphoid organs were examined 3 days after anamnestic stimulation with KLH or after primary injection of BGG. Light and electron microscopic study of the labeled cells revealed that immunologic memory resided in th...
متن کاملImmunologic Memory Cells of Bone Marrow Origin
Individual immunocompetent precursor cells of (C57BL/10 x C3H)F(1) mouse marrow generate, on transplantation, three to five times more antibody-forming cells localized in recipient spleens during secondary than during primary immune responses. The increased burst size is immunologically specific since antigens of horse and chicken erythrocytes and of Salmonella typhimurium do not cause this eff...
متن کاملImmunologic memory of phytohemagglutinin-stimulated lymphocytes.
By JEROME I. BRODY AND HENRY D. SOLTYS T HE PUBPOSE of this study was to delineate the durability and persistence of immunologic recall in the normal peripheral blood lymphocyte using methods which might reflect the importance of the manner by which imniunologic information is acquired. This was done in the present investigation with the technic of bacterial adherence,”2 in which circumferentia...
متن کاملDissecting the human immunologic memory for pathogens.
Studies on immunologic memory in animal models and especially in the human system are instrumental to identify mechanisms and correlates of protection necessary for vaccine development. In this article, we provide an overview of the cellular basis of immunologic memory. We also describe experimental approaches based on high throughput cell cultures, which we have developed to interrogate human ...
متن کاملImmunologic memory in Haemophilus influenzae type b conjugate vaccine failure.
AIMS To compare the convalescent antibody response to invasive Haemophilus influenzae type b (Hib) disease between conjugate vaccine immunised and unimmunised children, to look for evidence of priming for immunologic memory. METHODS Unmatched case-control study in the UK and Eire 1992-2001 and Victoria, Australia 1988-1990. A total of 93 children were identified as having invasive Hib disease...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1968
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.128.2.293